Understanding Lipogems® Technology: A Natural Approach to Healing

Fat Tissue Contains Powerful Healing Cells

Your body's fat tissue is much more than energy storage. It contains millions of special cells called pericytes and mesenchymal stem cells (MSCs). These cells live around tiny blood vessels throughout your fat tissue. When injury or inflammation occurs, these cells activate and release healing factors. Research shows fat tissue has far more of these regenerative cells than other body tissues. This makes it an ideal source for healing treatments.

Lipogems® Creates a "Living Graft" in Minutes

The Lipogems® system processes your own fat tissue using only gentle mechanical action. No enzymes or chemicals are used. The procedure takes less than twenty minutes from start to finish. The result is tiny fat clusters measuring about half a millimeter. These clusters keep their natural structure intact. This preserved structure acts as a scaffold that supports healing. The cells remain in their natural environment, which helps them work better and longer.

Your Body's Own "Mini-Drugstore" Supports Healing

When Lipogems® tissue is injected, the cells release helpful molecules over time. Scientists describe this as a "personalized drugstore" effect. These molecules reduce inflammation, fight infection, and prevent scarring. They also promote new blood vessel growth and protect cells from dying. This balanced response allows natural tissue repair without harsh interventions. The healing continues long after the injection because the transplanted tissue remains alive.

Studies Show Promising Results Across Many Conditions

Clinical applications span multiple medical fields with encouraging outcomes:

• Joint problems: Patients with knee, hip, and other joint conditions report significant pain relief. Some patients originally scheduled for surgery no longer needed it. X-rays and MRI scans taken six to eighteen months later showed possible cartilage regeneration.

• Wound healing: Chronic leg and foot ulcers, especially in diabetic patients, have healed using this approach.

• Reconstructive surgery: Facial procedures show faster recovery with less swelling and bruising compared to traditional fat grafting.

• Other applications: Anal fistulas and fecal incontinence treatments have shown impressive long-term tissue regeneration.

Mechanical Processing Outperforms Chemical Methods

Research comparing different preparation methods reveals important differences. Cells processed mechanically, like with Lipogems®, show better ability to develop into different tissue types. They also release a wider variety of helpful molecules. Their exosomes (tiny packages of healing signals) contain more beneficial contents. Chemical processing methods require hours or even weeks. They may also cause cells to age prematurely, reducing their effectiveness.

FDA-Cleared Technology Now Available Worldwide

The Lipogems® device received FDA clearance in 2014 as a class II medical device. A second clearance followed in 2016 specifically for arthroscopic (joint surgery) use. The technology is now approved in over twenty-three countries. Thousands of patients in both human and veterinary medicine have been treated safely. The system uses only your own tissue, eliminating donor rejection risks. Being minimally manipulated means it meets regulatory requirements without complex approval processes.

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This review presents Lipogems® as a practical advancement in regenerative medicine. The technology preserves natural healing elements while making the procedure quick and straightforward. For patients considering regenerative treatments, this approach offers a minimally invasive option using your body's own resources.

Source: Tremolada et al., None, 2017.