Understanding the Lipogems® Patent: Heart Sound Technology for Stem Cell Preparation

Your Own Fat Tissue Contains Powerful Healing Cells

If you're exploring options for tissue regeneration, you may have heard about treatments using your body's own cells. This patent describes the science behind Lipogems®, a technology that processes fat tissue to create a healing product rich in regenerative cells. The key insight is that fat tissue contains special cells called pericytes and mesenchymal stem cells (MSCs) that can help repair damaged tissues throughout your body.

No Embryos Needed: Adult Cells Do the Work

One important aspect of this technology is that it uses only adult cells from your own body. Unlike embryonic stem cells, which raise ethical concerns, the cells in this process come from your own fat tissue. These adult stem cells are called "multipotent," meaning they can transform into several different cell types to help with healing. The patent describes methods to enhance their regenerative potential without complex genetic engineering.

Heart Sounds May Help Guide Cell Development

Perhaps the most fascinating discovery in this patent involves the use of heart sounds. The inventors found that vibrations from heartbeat sounds can influence how stem cells develop. Since the heart is the first organ to form in an embryo, its rhythmic pulsing is present throughout our entire development. The researchers theorized that these natural vibrations act like an "orchestra conductor" for cell development, helping guide cells toward becoming the right tissue type.

A Simple Device Processes Fat Without Growing Cells in Labs

The patented device prepares what scientists call a "non-expanded tissue derivative." In plain terms, this means the fat tissue is processed mechanically without growing the cells artificially in a laboratory. This approach preserves the natural mixture of healing cells found in your fat tissue. The result is a product containing a "vascular-stromal fraction"—essentially a collection of cells that support blood vessels and tissue structure, enriched with stem cells and pericytes (helper cells that support blood vessel healing).

What This Means for Your Treatment Options

This patent represents the foundation of how Lipogems® works. When you receive a Lipogems® treatment, a small amount of fat is taken from your body through a minimally invasive procedure. That fat is then processed using this patented technology to create micro-fragmented adipose tissue (specially processed fat tissue) that can be injected into areas needing repair.

The key benefits described in this patent include:

• Using your own tissue reduces the risk of rejection or allergic reactions

• No laboratory cell expansion means a same-day procedure is possible

• Preserving natural cell relationships keeps the healing environment intact

• The vibration technology may help optimize the cells' regenerative potential

FDA-Cleared Technology Backed by Research

This 2020 U.S. patent adds to the growing body of evidence supporting Lipogems® technology. With over 175 peer-reviewed publications and more than 105,000 successful orthopedic cases worldwide, this approach has moved from laboratory concept to clinical reality. The technology is FDA cleared and used by leading medical institutions globally for conditions including joint injuries, osteoarthritis, and chronic pain.

If you're considering regenerative treatment for tissue damage, this patent shows that Lipogems® is built on innovative science designed to harness your body's own healing abilities in a safe, minimally invasive way.

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Source: Tremolada et al., United States Patent, 2020.