
Regenerative Medicine
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When ankle pain limits freedom of movement and compromises quality of life, finding an effective solution becomes a priority. Many patients approach the world of infiltrative therapies seeking information about hyaluronic acid injections, often considered the first conservative approach to treating osteoarthritis or joint trauma.
At IMAGE REGENERATIVE, we deeply understand this need, but our clinical experience has led us to evolve the concept of care. While traditional injections represent a valid standard for symptomatic relief, our clinical experience focuses on advanced regenerative medicine.
Through orthopedic Lipogems®, we aim to repair damaged tissues from within, offering a prospect of natural and lasting healing that surpasses the limits of conventional symptomatic treatments.
Hyaluronic acid is a polysaccharide naturally present in the human body, essential for maintaining tissue hydration and elasticity. In joints, it acts as a lubricant and shock absorber, allowing bones to slide over each other without friction and protecting cartilage from wear.
With aging or following trauma, natural production of this substance decreases, leading to stiffness and pain. In traditional orthopedics, hyaluronic acid is synthesized in the laboratory and used for viscosupplementation, that is, to replenish the fluid component of the joint.
However, it is essential to understand that, despite its hydrating properties, injected hyaluronic acid is a resorbable material that the body metabolizes within a few months, making its effect limited in time and purely symptomatic.
The use of hyaluronic acid in ankle injections arises from the need to reduce joint friction in patients with osteoarthritis or chondropathy. The primary objective of this treatment is mechanical: to improve the sliding of articular surfaces and temporarily reduce inflammation associated with friction.
It is often proposed as a bridge solution to delay more invasive surgical interventions or to manage pain in acute phases. However, this approach presents a significant intrinsic limitation: it acts on the consequences of the pathology (pain and poor lubrication) without intervening on the biological causes of tissue degeneration.
In contrast, our clinical philosophy favors interventions that actively stimulate tissue repair, which is why we consider regenerative therapies with autologous adipose tissue a more evolved choice for those seeking concrete and long-term results.
The standard procedure for hyaluronic acid injections involves direct injection of the substance into the joint capsule of the ankle. After disinfecting the area, the physician uses a syringe to introduce the viscous gel into the intra-articular space. Although it is a relatively simple outpatient procedure, it requires precision to avoid damaging surrounding structures.
At IMAGE REGENERATIVE, we have elevated the standard of these interventional procedures. When we perform our Lipogems® regenerative treatment, we use guided infiltration techniques, often with ultrasound or fluoroscopic support, to ensure that the precious regenerative tissue reaches the site of damage with millimeter precision.
This level of precision is essential to maximize treatment effectiveness and ensure maximum patient comfort.
Traditional hyaluronic acid injections generally offer pain reduction and improved mobility that can last from 3 to 6 months. This temporary relief is appreciable, but forces the patient to undergo continuous injection cycles to maintain the benefit.
It is interesting to note how the same limitations are found in the treatment of other complex joints, such as the knee, where cartilage wear often requires more incisive solutions.
Precisely to overcome the transitory nature of these results, we have chosen to focus on regenerative medicine. While hyaluronic acid merely "oils" the mechanism, Lipogems® treatment harnesses the mesenchymal cells present in the patient's adipose tissue to trigger a real tissue regeneration process.
The benefits we observe in our patients include a profound reduction in inflammation that can last for years, surpassing the limited time window of traditional treatments. The advanced effectiveness of the regenerative approach lies in its ability to treat the biological cause of pain, offering a significantly superior quality of life and preventing osteoarthritis progression.
Characteristic | Hyaluronic Acid Injections (Traditional) | Lipogems® Treatment (IMAGE REGENERATIVE) |
Action | Mechanical and lubricating (viscosupplementation) | Biological and regenerative (tissue repair) |
Duration of Results | Temporary (3-6 months) | Long-term (up to 3-5 years) +2 |
Origin | Synthetic or animal-derived | Autologous (patient's adipose tissue) |
Objective | Symptom management (pain) | Treating the cause and regeneration |
Potential | No regenerative capacity | High regenerative potential thanks to mesenchymal cells |

After an ankle injection, a brief period of relative rest is generally recommended to allow the product to distribute in the joint. However, with the regenerative protocol we adopt, recovery takes on a different meaning. Since we use the patient's own tissue, the risk of adverse reactions or rejection is virtually zero.
We advise our patients to follow a gradual resumption program, often supported by personalized physiotherapy indications, to maximize the integration of regenerative tissue.
The advantage of Lipogems® treatment is that, being a minimally invasive procedure performed in a single session, it allows a rapid return to daily activities, with the awareness of having invested in a solution that will actively work in the body for months and years to come, progressively improving joint health.
The lubricating effect of hyaluronic acid is almost immediate, but pain relief may take several days. In contrast, Lipogems® regenerative treatment triggers a biological repair process that leads to progressive and constant improvement, with benefits that aim to consolidate in the long term.
The injection can cause slight distension discomfort. At IMAGE REGENERATIVE, we use guided infiltration techniques and local anesthesia for adipose tissue harvesting in the Lipogems® protocol, ensuring a comfortable and virtually painless experience for the patient.
The technique involves inserting a needle into the joint space. In our advanced protocol, this phase is preceded by painless harvesting of a small amount of adipose tissue, which is then processed and infiltrated with ultrasound guidance to ensure that the regenerative potential reaches exactly the damaged area.
Usually 24-48 hours of relative rest are recommended. With Lipogems® treatment, the patient can go home on the same day and resume normal activities in a short time, benefiting from accelerated recovery thanks to the natural anti-inflammatory properties of their own tissue.
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